Gene interactions and pathways from curated databases and text-mining

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IL8 — LTB

Text-mined interactions from Literome

Denizot et al., Cytokine 1999 : LTB ( 4 ) ( 1 microM ) enhances IL-8 production only in serum supplemented medium
Chang et al., Exp Cell Res 2002 : Lymphotoxin beta receptor induces interleukin 8 gene expression via NF-kappaB and AP-1 activation
Wirthmueller et al., Biochem Biophys Res Commun 1991 : NAP-1/IL-8 does not induce the synthesis of PAF and LTB4 from endogenous phospholipid precursors, even after preincubation with GM-CSF
Nam et al., Inflamm Res 2012 (Trichomonas Infections) : We investigated whether LTB ( 4 ) contained in the T. vaginalis derived secretory products ( TvSP ) is closely involved in interleukin (IL)-8 production in human neutrophils via LTB ( 4 ) receptors BLT1 or BLT2 ... Our results suggest that LTB ( 4 ) receptors BLT1 and BLT2 are involved in IL-8 production in neutrophils induced by T. vaginalis
Rola-Pleszczynski et al., Union Med Can 1989 : In particular, LTB4 can induce suppressor cells, activate the synthesis and production of lymphokines such as interleukin 2 or interferon-gamma, stimulate the production of interleukin 1 by monocytes or macrophages, and activate cytotoxic cells against virus infected or tumor target cells
Schröder et al., J Exp Med 1989 : In the presence of 8 x 10 ( -9 ) mol/liter [ 3H ] AA, NAP/IL-8 ( 10 ( -9 ) to 10 ( -7 ) mol/liter ) did not induce the production of LTB4, omega oxidized LTB4 , or 5-HETE
McCain et al., Am J Respir Cell Mol Biol 1994 : Here we examine whether PMN synthesize and release IL-8 in response to stimulation by leukotriene B4 (LTB4)
Frieri et al., Ann Allergy Asthma Immunol 1998 (Asthma...) : Leukotriene B4 (LTB4) , a potent chemokinetic mediator for neutrophils, is enhanced by interleukin-8 (IL-8) and may play a key role in the inflammatory response of asthma