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IL8 — LTB
Text-mined interactions from Literome
Denizot et al., Cytokine 1999
:
LTB ( 4 ) ( 1 microM )
enhances IL-8 production only in serum supplemented medium
Chang et al., Exp Cell Res 2002
:
Lymphotoxin beta receptor induces
interleukin 8 gene expression via NF-kappaB and AP-1 activation
Wirthmueller et al., Biochem Biophys Res Commun 1991
:
NAP-1/IL-8 does not
induce the synthesis of PAF and
LTB4 from endogenous phospholipid precursors, even after preincubation with GM-CSF
Nam et al., Inflamm Res 2012
(Trichomonas Infections) :
We investigated whether
LTB ( 4 ) contained in the T. vaginalis derived secretory products ( TvSP ) is closely
involved in
interleukin (IL)-8 production in human neutrophils via LTB ( 4 ) receptors BLT1 or BLT2 ... Our results suggest that
LTB ( 4 ) receptors BLT1 and BLT2 are
involved in
IL-8 production in neutrophils induced by T. vaginalis
Rola-Pleszczynski et al., Union Med Can 1989
:
In particular,
LTB4 can induce suppressor cells, activate the synthesis and production of lymphokines such as interleukin 2 or interferon-gamma,
stimulate the production of
interleukin 1 by monocytes or macrophages, and activate cytotoxic cells against virus infected or tumor target cells
Schröder et al., J Exp Med 1989
:
In the presence of 8 x 10 ( -9 ) mol/liter [ 3H ] AA,
NAP/IL-8 ( 10 ( -9 ) to 10 ( -7 ) mol/liter ) did not
induce the production of LTB4, omega oxidized
LTB4 , or 5-HETE
McCain et al., Am J Respir Cell Mol Biol 1994
:
Here we examine whether PMN synthesize and release
IL-8 in
response to stimulation by
leukotriene B4 (LTB4)
Frieri et al., Ann Allergy Asthma Immunol 1998
(Asthma...) :
Leukotriene B4 (LTB4) , a potent chemokinetic mediator for neutrophils, is
enhanced by
interleukin-8 (IL-8) and may play a key role in the inflammatory response of asthma