Gene interactions and pathways from curated databases and text-mining

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HBEGF — IL8

Text-mined interactions from Literome

Mehta et al., J Immunol 2003 (Inflammation) : HB-EGF dramatically suppressed NF-kappaB activity and IL-8 release and decreased NO production in cells pretreated with HB-EGF
Tanida et al., Digestion 2010 : Here, we focus on the mechanisms of IL-8 induced HB-EGF-CTF signaling, which is involved in cytoprotection and cellular repair
Lee et al., Arterioscler Thromb Vasc Biol 2012 (Atherosclerosis) : The silencing and overexpression of HBEGF in HAECs confirmed the role of HBEGF in regulating IL-8 expression