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ETS1 — MMP3
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Westermarck et al., FASEB J 1999
(Neoplasm Invasiveness...) :
This review will summarize the current view on the role of MMPs in tumor growth, invasion, and survival, and focus on the
role of mitogen activated protein kinases and AP-1 and
ETS transcription factors in the regulation of
MMP gene expression during invasion process
Igarashi et al., Tohoku J Exp Med 2001
:
The transcription factor
ETS-1 expressed in endothelial cells ( ECs )
regulates angiogenesis by inducing MMP-1,
MMP-3 , MMP-9, u-PA and integrin beta3 in endothelial cells ( ECs )
Kondo et al., Int J Cancer 2005
(Carcinoma, Squamous Cell...) :
LMP1 transfected cells with 2G/2G genotype expressed MMP1, which was abolished by activator protein-1 (AP1) dominant negative ( DN ) and Ets-DN. LMP1 also induced active
MMP3 , which can cleave latent MMP1, and AP1-DN and
Ets-DN suppressed the MMP3 expression
Furlan et al., J Cell Physiol 2008
(Mammary Neoplasms, Animal...) :
Moreover,
Ets-1 concomitantly
triggered matrix metalloproteinases ( MMP ) expression and activation, thus contributing to cell scattering
Park et al., Biochem Biophys Res Commun 2008
(Breast Neoplasms) :
The expression of
matrix metalloproteinase ( MMP ) genes was
enhanced by the overexpression of
HER2/Ets-1
Heo et al., J Cell Physiol 2010
:
In addition,
MMP-10 transcription was
mediated by
Ets-1 but not ERP/NET/ELK3