Gene interactions and pathways from curated databases and text-mining

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CD46 — STAT3

Text-mined interactions from Literome

Buettner et al., Mol Cancer Res 2007 (Breast Neoplasms...) : CD46 promoter activity is induced by activation of STAT3 and blocked by a dominant negative form of STAT3 in luciferase reporter assays ... Furthermore, we show that inhibition of STAT3 mediated CD46 cell surface expression sensitizes DU145 prostate cancer cells to cytotoxicity in an in vitro complement lysis assay using rabbit anti-DU145 antiserum and rabbit complement
Ray et al., Nucleic Acids Res 2008 : We have found that HDAC1 knockdown also interferes with the responsiveness of the STAT3 dependent MCP1 target gene expression to IL-6, as confirmed by real-time RT-PCR analysis