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CXCL12 — TIMP1

Text-mined interactions from Literome

Damås et al., Circulation 2002 (Angina, Unstable) : In vitro, SDF-1alpha ( 500 ng/mL ) reduced both unstimulated and endotoxin/mitogen stimulated mRNA and protein levels of monocyte chemoattractant protein-1, interleukin-8, matrix metalloproteinase-9, and tissue factor while increasing tissue inhibitor of metalloproteinases-1 in PBMC from patients with unstable angina
Ries et al., Blood 2007 (Inflammation) : Moreover, the inflammatory cytokines TGF-beta1, IL-1beta, and TNF-alpha up-regulated MMP-2, MT1-MMP, and/or MMP-9 production in these cells, resulting in a strong stimulation of chemotactic migration through ECM, whereas the chemokine SDF-1alpha exhibited minor effects on MMP/TIMP expression and cell invasion