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CALM3 — CDK2

Text-mined interactions from Literome

Choi et al., Circ Res 2006 : Taken together, these findings reveal CaM dependent cyclin E/CDK2 activity as a mediator of the known Ca2+ sensitivity of the G1/S transition of VSMC
Choi et al., Cell cycle (Georgetown, Tex.) 2006 : Having identified a CaM binding site on cyclin E1, our studies support a direct role for CaM in mediating Ca2+-sensitive cyclin E/CDK2 activity and G1 to S phase transitions in VSMC
Hui et al., Circ Res 2011 (Coronary Restenosis...) : Having discovered that calmodulin (CaM) dependent cyclin E/CDK2 activity underlies Ca ( 2+ ) -sensitive G ( 1 ) -to-S phase transitions in VSMCs, we sought to explore the physiological importance of the CaM-cyclin E interaction ... A synthetic peptide designed to disrupt CaM-cyclin E binding inhibits Ca ( 2+ ) /CaM dependent CDK2 activity, cell cycle progression, and proliferation in VSMCs and limits arterial remodeling following injury