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IL8 — KLK3
Text-mined interactions from Literome
Mazmanian et al., Nature 2008
(Colitis...) :
Purified
PSA administered to animals is
required to suppress pro-inflammatory
interleukin-17 production by intestinal immune cells and also inhibits in vitro reactions in cell cultures
Yuan et al., World J Gastroenterol 2009
(MAP Kinase Signaling System) :
APS did not block the activation of extracellular signal regulated kinase or c Jun amino-terminal kinase, but inhibited the activation of p38, suggesting that
APS inhibits LPS induced production of TNF-alpha and
IL-8 mRNAs, possibly by suppressing the p38 signaling pathway