Gene interactions and pathways from curated databases and text-mining

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IL8 — KLK3

Text-mined interactions from Literome

Mazmanian et al., Nature 2008 (Colitis...) : Purified PSA administered to animals is required to suppress pro-inflammatory interleukin-17 production by intestinal immune cells and also inhibits in vitro reactions in cell cultures
Yuan et al., World J Gastroenterol 2009 (MAP Kinase Signaling System) : APS did not block the activation of extracellular signal regulated kinase or c Jun amino-terminal kinase, but inhibited the activation of p38, suggesting that APS inhibits LPS induced production of TNF-alpha and IL-8 mRNAs, possibly by suppressing the p38 signaling pathway