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CAT — IGF1
Text-mined interactions from Literome
Germinario et al., AIDS Res Hum Retroviruses 1999
:
Using COS 7 cells cotransfected with tat and an HIV LTR linked to a chloramphenicol acetyltransferase (CAT) reporter, we observed that physiological levels of
IGF-I ( 10 ( -9 ) M ) significantly
inhibited CAT expression in a concentration- and time dependent manner ...
IGF-I did not inhibit CAT expression in COS 7 cells transfected with pSVCAT, and did not
affect CAT expression in the absence of cotransfection with tat
Brown-Borg et al., Experimental biology and medicine (Maywood, N.J.) 2002
:
A 41 % and 27 % decrease in
catalase activity was
detected in cells treated with GH, whereas
IGF-1 reduced CAT activity levels to a greater extent than GH ( P < 0.0001 )
Flint et al., Domest Anim Endocrinol 2002
:
The effect of IGF-I occurred within an hour, before any detectable increase in cell proliferation, and the activation of
CAT expression in
response to
IGF-I or EGF was blocked by U 0126 ... In stromal cells, the fact that U 0126 blocked the
CAT responses to
IGF-I and EGF indicates the involvement of a MAP kinase