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CXCL12 — TP53
Text-mined interactions from Literome
Moskovits et al., Cancer Res 2006
(Neoplasm Invasiveness...) :
We now report that
p53 can
suppress the production of the chemokine
SDF-1 in cultured fibroblasts of both human and mouse origin
Kojima et al., Blood 2011
(Leukemia, Myeloid, Acute) :
p53 activation by Nutlin-3a was not cytotoxic to stromal cells, but
reduced CXCL12 mRNA levels and secretion of CXCL12 partially through p53 mediated HIF-1a down-regulation
Panka et al., Molecular cancer 2013
(Carcinoma, Renal Cell) :
Effects of HDM2 antagonism on sunitinib resistance,
p53 activation,
SDF-1 induction , and tumor infiltration by CD11b+/Gr-1+ myeloid derived suppressor cells