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MMP2 — SLC22A3

Text-mined interactions from Literome

Stallings-Mann et al., Cells Tissues Organs 2007 (Cell Transformation, Neoplastic) : We have identified the induction of Rac1b, an alternatively spliced variant of Rac1, as a key event in MMP induced EMT
Lee et al., Carcinogenesis 2008 (Breast Neoplasms...) : Fibulin-5 initiates epithelial-mesenchymal transition (EMT) and enhances EMT induced by TGF-beta in mammary epithelial cells via a MMP dependent mechanism
Tan et al., Am J Pathol 2010 (Fibrosis...) : AMCM induced tubular cell EMT in C1.1 cells was inhibited by broad-spectrum MMP inhibitor ( GM6001 ), MMP-2/9 inhibitor, and in AMCM after MMP-9 removal by monoclonal Ab against MMP-9 ... AMCM induced EMT in primary tubular epithelial cells was inhibited by MMP-2/9 inhibitor ... Furthermore, MMP-9 induced tubular cell EMT in C1.1 cells to an extent similar to transforming growth factor-beta
Liu et al., J Invest Dermatol 2012 (Melanoma...) : Supplementing MMP-2 to culture media did not induce EMT , suggesting that EMT induction by Nox1 was not through MMP-2 upregulation ... In summary, Nox1 was overexpressed in all melanoma cell lines examined, and enhanced cell invasion by MMP-2 upregulation and EMT induction