Gene interactions and pathways from curated databases and text-mining

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IL8 — ST8SIA2

Text-mined interactions from Literome

Berin et al., Cell Microbiol 2002 (MAP Kinase Signaling System) : Isogenic eae- and stx- mutants also activated p38 and ERK MAP kinases, and NF-kappaB and stimulated increases in IL-8 protein secretion similar to those of wild-type EHEC
Smith et al., Infect Immun 2003 : We have previously shown that Stxs can induce multiple C-X-C chemokines in intestinal epithelial cells in vitro, including interleukin-8 (IL-8), and that Stx induced IL-8 expression is linked to induction of c-Jun mRNA and p38 mitogen activated protein ( MAP ) kinase pathway activity
Yamasaki et al., Biochim Biophys Acta 2004 : IL-8 production was enhanced by Stx , ricin, and modeccin, three toxins that inhibit protein synthesis through an identical RNA N-glycosidase activity, but not by two other types of protein synthesis inhibitors, diphtheria toxin and cycloheximide
Gray et al., Toxicological sciences : an official journal of the Society of Toxicology 2008 : The purpose of this study was to test the hypothesis that PKR is essential for induction of interleukin (IL)-8 expression in monocytes by DON and two prototypical RIPs, ricin, and Shiga toxin 1 (Stx1)