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EGF — GSK3A
Text-mined interactions from Literome
Shaw et al., FEBS Lett 1999
(MAP Kinase Signaling System) :
Here, we show that protein kinase B (PKB) plays a key role in mediating
EGF induced inhibition of
GSK3alpha and that the classical MAP kinase ( MAPK ) cascade has two functions in this process ... Firstly, it makes a transient contribution to
EGF induced inhibition of
GSK3alpha
Saito et al., Biochem J 1994
:
EGF stimulation of A431 cells
inhibited GSK3 alpha and GSK3 beta to a similar extent, and inhibition was accompanied by phosphorylation of the tryptic peptides containing the serine residues phosphorylated in vitro by p70 S6 kinase or MAP kinase activated protein ( MAPKAP ) kinase-1 beta ( also termed Rsk-2 )