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EPHB2 — TRPV1
Text-mined interactions from Literome
Bron et al., Mol Cell Neurosci 2003
(Pain) :
Constitutive simultaneous stimulation of both
ERK and phosphatidylinositol 3-kinase is not
sufficient for
VR1 upregulation
Katsura et al., J Neurochem 2007
(Hyperalgesia...) :
Furthermore, the inhibition of
ERK5 blocked the induction of transient receptor potential channel
TRPV1 and TRPA1 expression in DRG neurons after peripheral inflammation
Chen et al., Osteoarthritis Cartilage 2009
(Arthritis, Experimental...) :
Vanilloid receptor
TRPV1 mediated phosphorylation of
ERK in murine adjuvant arthritis ... One possibility is that downstream effects of activation of
TRPV1 are
mediated by the
extracellularly regulated kinase (ERK)
Li et al., Brain Res Bull 2008
(Hyperesthesia...) :
These results suggest that activation of the ERK signaling pathway in the periphery is likely necessary for maintenance of a spinally sensitized state ; activation of
ERK1/2 in the primary injury site may
regulate TRPV1 , leading to dorsal horn hypersensitivity to thermal and chemical stimuli
Cong et al., J Cell Sci 2013
:
Mechanistically,
TRPV1 activation
increased ERK1/2 and MLC2 phosphorylation ... Mechanistically,
TRPV1 activation
increased ERK1/2 and MLC2 phosphorylation