◀ Back to MAPK7
MAPK7 — SGK1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
SGK1
—
MAPK7
(direct interaction, two hybrid)
Hayashi et al., J Biol Chem 2001*
-
IRef Biogrid Interaction:
SGK1
—
MAPK7
(direct interaction, enzymatic study)
Hayashi et al., J Biol Chem 2001*
-
IRef Biogrid Interaction:
SGK1
—
MAPK7
(direct interaction, pull down)
Hayashi et al., J Biol Chem 2001*
-
IRef Hprd Interaction:
SGK1
—
MAPK7
(in vivo)
Hayashi et al., J Biol Chem 2001*
-
IRef Hprd Interaction:
SGK1
—
MAPK7
(two hybrid)
Hayashi et al., J Biol Chem 2001*
-
IRef Hprd Interaction:
SGK1
—
MAPK7
(in vitro)
Hayashi et al., J Biol Chem 2001*
-
IRef Ophid Interaction:
SGK1
—
MAPK7
(aggregation, confirmational text mining)
Hayashi et al., J Biol Chem 2001*
-
IRef Ophid Interaction:
SGK1
—
MAPK7
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Gonzalez-Robayna et al., Mol Endocrinol 2000
:
In contrast, FSH induction and phosphorylation of
Sgk protein requires A kinase ( H89 sensitive ) but also
involves PI3-K ( LY294002 sensitive ) as well as
p38MAPK ( SB203580 sensitive ) pathways
Hayashi et al., J Biol Chem 2001
:
During growth factor induced cell stimulation,
BMK1 activates
SGK by phosphorylation at serine 78
Meng et al., Am J Physiol Cell Physiol 2005
:
Overexpression of p38alpha increased constitutive SGK phosphorylation at Ser78, whereas dominant negative p38alpha
MAPK blocked IL-6 induced
SGK phosphorylation and nuclear translocation
BelAiba et al., Circ Res 2006
(Hypertension, Pulmonary) :
These data show that thrombin potently induces Sgk-1 involving NADPH oxidases, phosphatidylinositol 3-kinase, p38
mitogen activated protein kinase , and phosphoinositide dependent kinase-1, and that
activation of nuclear factor kappaB by
Sgk-1 mediates TF expression and activity by thrombin
Notch et al., Comp Biochem Physiol A Mol Integr Physiol 2012
:
To test the hypothesis that
mitogen activated protein kinase ( MAPK14 ) is
responsible for the rise in
SGK1 we identified the coding sequence of killifish MAPK14-1 and designed a translational blocking vivo-morpholino targeting MAPK14-1