Gene interactions and pathways from curated databases and text-mining

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GP2 — IRF6

Text-mined interactions from Literome

Slomiany et al., Biochem Biophys Res Commun 2002 (MAP Kinase Signaling System) : Inhibition of extracellular signal regulated kinase ( ERK ) with PD98059 accelerated the LPS induced decrease in the glycoprotein synthesis and caused further increase in apoptosis and NOS-2 activity, while the blockade of p38 mitogen activated kinase ( MAPK ) with SB203580 countered the LPS induced reduction in the glycoprotein synthesis and obviated the induced increases in NOS-2 and apoptosis
Myers et al., Am J Physiol 1992 : Intercellular adhesion molecule 1 ( ICAM-1 ) is a proinflammatory adhesion glycoprotein induced by cytokines such as interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) as well as lipopolysaccharide (LPS)
Heemskerk et al., J Biomed Biotechnol 2010 : Regulation of P-glycoprotein in renal proximal tubule epithelial cells by LPS and TNF-alpha
Cardoso et al., PloS one 2012 : LPS and UCB led to inhibition of P-glycoprotein and activation of matrix metalloproteinases-2 and -9 in mono-cultures
Dallas et al., Journal of neuroinflammation 2013 (HIV Infections) : LPS did not directly inhibit saquinavir transport, and did not affect P-glycoprotein protein expression
Bloise et al., PloS one 2013 : Lipopolysaccharide (LPS) in high doses inhibits placental multidrug resistance P-glycoprotein ( P-gp - Abcb1a/b ) and breast cancer resistance protein ( BCRP - Abcg2 )
Bories et al., Biochem Biophys Res Commun 1987 : LPS or LPS receptors were not involved in the activity of alpha 1-acid glycoprotein on macrophages
Yu et al., Chin Med Sci J 1995 : The results showed that : 1 ) LPS increased the binding of fibrinogen-gold complexes to platelets and the labels were primarily limited to shape changed platelets ; 2 ) LPS caused a dose dependent rise in intracellular Ca2+ concentration in platelets ; 3 ) LPS induced the activation of platelet protein kinase C ( PKC ) and the phosphorylation of glycoprotein llla ( GPllla ) which was inhibited by H-7
Lei et al., J Biol Chem 1993 : The binding of PT to LPS can be inhibited by bovine fetuin glycoprotein
Eastman et al., Shock 1996 (Acute-Phase Reaction) : Induction of hemopexin, alpha 1-acid glycoprotein , alpha 2-macroglobulin, GADD153, C/EBP beta, and C/EBP delta mRNAs by LPS were all abolished in dexamethasone treated rats