UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

ETS2 — IRF6

Text-mined interactions from Literome

Takahashi et al., Mol Cell Biochem 2001 : Electrophoretic mobility shift assay revealed that LPS augmented the nuclear protein bindings to the Ets/PEA3 as well as kappaB motifs
Chung et al., J Biol Chem 2005 (Inflammation) : A potent inflammatory mediator, bacterial lipopolysaccharide (LPS) , induced Ets-2 at the mRNA and protein level, and this induction preceded the up-regulation of HO-1
Chung et al., J Cell Physiol 2012 (Inflammation) : This EBS is known to be important for Ets-2 transactivation of HO-1 by LPS stimulation, and we show that TGF-ß1 is able to suppress LPS induced Ets-2 mRNA and protein levels in macrophages
Boulukos et al., Genes Dev 1990 : Rapid and transient expression of Ets2 in mature macrophages following stimulation with cMGF, LPS , and PKC activators
Groupp et al., J Biol Chem 1996 : These data suggest that LPS stimulation of THP-1 cells activates binding of c-Jun, Ets , and Egr-1 to the TF promoter and implicates these factors in the transcriptional activation of TF mRNA synthesis