◀ Back to HNRNPF
HNRNPF — KITLG
Text-mined interactions from Literome
Feng et al., Stem Cells 2000
:
A large number of cells with the morphological, phenotypical, and functional characteristics of DCs was generated from both c-kit ( low ) and c-kit ( low ) populations when cultured with a combination of cytokines ( GM-CSF, tumor necrosis factor-a [TNF-a ], interleukin 7 [IL-7 ], IL-3, stem cell factor [ SCF ], and flt3 ligand ) ; the cytokine combination studies revealed that
SCF and IL-3 in addition to GM-CSF and TNF-a are
essential for
DCs to be generated from these primitive populations
Siena et al., Exp Hematol 1995
(Neoplasms) :
We show that the GM-CSF-plus-TNF-alpha dependent ex vivo generation of
DCs from mobilized CD34+ cells is 2.5-fold
enhanced by flk-2/flt-3 ligand or
c-kit ligand ( stem cell factor ) and five-fold enhanced by a combination of these growth factors