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MAPK1 — P2RY2
Text-mined interactions from Literome
Gao et al., J Biol Chem 1999
:
A2B adenosine and
P2Y2 receptors
stimulate mitogen activated protein kinase in human embryonic kidney-293 cells
Liu et al., J Biol Chem 2004
(Astrocytoma) :
A mutant
P2Y(2) receptor lacking the PXXP motifs was found to stimulate calcium mobilization and serine/threonine phosphorylation of the
Erk1/2 mitogen
activated protein kinases, like the wild-type receptor, but was defective in its ability to stimulate tyrosine phosphorylation of Src and Src dependent tyrosine phosphorylation of the proline-rich tyrosine kinase 2, epidermal growth factor receptor (EGFR), and platelet derived growth factor receptor
Morris et al., Am J Physiol Cell Physiol 2012
(Hypertension) :
These data highlight a differential arrestin dependent regulation of ET ( A ) and
P2Y(2) receptor
stimulated MAPK signaling
Patel et al., Biochem J 1996
:
2-Methylthio-ATP and UTP, selectively activating P2Y1 and
P2Y2 purinoceptors respectively, and ATP, a non-selective agonist at these two receptors,
stimulate the tyrosine phosphorylation of both
p42mapk and p44mapk, as revealed by Western blots with an antiserum specific for the tyrosine phosphorylated forms of the enzymes
Soltoff et al., J Biol Chem 1998
:
Related adhesion focal tyrosine kinase and the epidermal growth factor receptor mediate the
stimulation of
mitogen activated protein kinase by the G-protein coupled
P2Y2 receptor