Andrews et al., J Biol Chem 2002
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Northern blot analysis revealed that a subset of the identified targets including IRF-7, MxA, and ISG-54 were synergistically up-regulated by BRCA1 in the presence of interferon gamma (IFN-gamma) but not interferons alpha or beta
Buckley et al., Mol Cancer Res 2007
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BRCA1 regulates IFN-gamma signaling through a mechanism involving the type I IFNs ... Using an Affymetrix U95A microarray, IRF-7 was identified as a BRCA1 transcriptional target and was also shown to be synergistically up-regulated by BRCA1 specifically in the presence of IFN-gamma , coincident with the synergistic induction of apoptosis