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ECM1 — EPHB2

Text-mined interactions from Literome

Tsang et al., Int J Oncol 2001 : The results of these experiments indicate that induction of hypophosphorylated ets-1 as the result of RA and ECM mediated decreases in ERK1 activity represents a novel mechanism by which RA regulates MMP-9 gene expression
Salasznyk et al., Cell communication & adhesion 2004 (MAP Kinase Signaling System) : We found that addition of beta1 and alpha(v)beta3 integrin blocking antibodies inhibited ECM induced ERK activation, while addition of the MEK inhibitor PD98059 blocked ERK activation, serine phosphorylation of the osteogenic transcription factor runx2/cbfa-1, osteogenic gene expression, and calcium deposition
Ha et al., Life Sci 2006 : Inhibitor of ERK or p38 MAPK suppressed PDGF induced MC proliferation and ECM synthesis
Salasznyk et al., Exp Cell Res 2007 (MAP Kinase Signaling System) : We hypothesized that FAK signaling pathways provide a link between activation of ERK1/2 by ECM , and stimulate subsequent phosphorylation of the Runx2/Cbfa-1 transcription factor that controls osteogenic gene expression ... We found that siRNA treatment reduced FAK mRNA levels by > 40 % and decreased ECM mediated phosphorylation of FAK Y397 and ERK1/2
Kang et al., Int J Mol Med 2008 (Cell Transformation, Neoplastic) : ECM from fibroblasts in UVB-SIPS activates FAK, ERK , and AKT in HaCaT cells ... ERK and PI3K/AKT inhibitors inhibit ECM induced ERK , AKT activation and cell proliferation
Dorado et al., Nephrol Dial Transplant 2008 : These results suggest that Erk5 is involved in agonist induced mesangial cell contraction, proliferation and ECM accumulation and point to a multifunctional role of Erk5 in the pathophysiology of glomerular mesangial cells
Urushihara et al., American journal of physiology. Renal physiology 2010 (Disease Models, Animal...) : Taken together, these results suggest that MC ERK5 phosphorylation by ANG II or H ( 2 ) O ( 2 ) enhances cell viability and ECM accumulation in an experimental model of chronic GN
Hamamura et al., Cell Biol Int 2010 : ECM dependent mRNA expression profiles and phosphorylation patterns of p130Cas, FAK, ERK and p38 MAPK of osteoblast-like cells
Hu et al., Arch Dermatol Res 2013 (Cicatrix, Hypertrophic...) : The role of ERK and JNK signaling in connective tissue growth factor induced extracellular matrix protein production and scar formation