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AKT1 — FYN

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• STRING interaction: AKT1 — FYN (interaction, mapped from kegg_pathways)
• STRING interaction: AKT1 — FYN (interaction, mapped from kegg_pathways)
• STRING interaction: FYN — AKT1 (interaction, mapped from bind kegg_pathways dip)
• STRING interaction: FYN — AKT1 (interaction, mapped from bind kegg_pathways dip)

Text-mined interactions from Literome

Ballif et al., Brain Res Mol Brain Res 2003 : Additionally, although Fyn is an important regulator of Dab1, Fyn deficiency does not prevent acute Reelin induced Akt activation
Abramson et al., EMBO J 2006 : Specifically, MAFA suppresses the PLC-gamma2- [ Ca2+ ] i, Raf-1-Erk1/2, and PKC-p38 coupling pathways, while the Fyn-Gab2 mediated activation of PKB and Jnk is essentially unaffected
Wang et al., J Biol Chem 2010 (Wounds and Injuries) : Engagement of LN332 or clustering of the alpha6beta4 integrin with integrin-specific antibodies causes phosphorylation of ErbB2, Fyn , and the beta4 subunit as well as activation of phosphatidylinositol 3-kinase and Akt and their assimilation into this complex
Yadav et al., Mol Carcinog 2011 : Fyn is induced by Ras/PI3K/Akt signaling and is required for enhanced invasion/migration ... Activation of Akt , but not MAPK or EGFR, was necessary and sufficient for induction of Fyn by H-Ras
Hatton et al., PloS one 2012 (Lymphoma, B-Cell) : Whereas Src kinases are often required for Syk activation, we show here that PI3K/Akt activation and autocrine IL-10 production by NGFR-LMP1 involves the Src family kinase Fyn
Zhang et al., PloS one 2012 (Diabetes Mellitus, Experimental...) : Zn is required for maintaining Akt activation by inhibiting the expression of Akt negative regulators ; Akt activation can inhibit Fyn nuclear translocation to export nuclear Nrf2 to cytoplasm for degradation