Gene interactions and pathways from curated databases and text-mining

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AHR — NR1I2

Text-mined interactions from Literome

Sugatani et al., Naunyn Schmiedebergs Arch Pharmacol 2008 (Hyperbilirubinemia) : A 290-bp distal enhancer module, phenobarbital-responsive enhancer module of UGT1A1 ( gtPBREM ), fully accounts for constitutive androstane receptor (CAR)-, pregnane X receptor (PXR)- , glucocorticoid receptor ( GR ) -, and aryl hydrocarbon receptor (AhR) mediated activation of the UGT1A1 gene
Kumagai et al., Drug Metab Pharmacokinet 2012 : Here we demonstrate that the AhR activators induce CYP3A4 through human pregnane X receptor (PXR)