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TP53 — TRIM26

Text-mined interactions from Literome

Arima et al., Int J Mol Med 2002 (Carcinoma, Hepatocellular...) : These results suggest that HBX interacts with p53 to up-regulate AFP gene transcription probably by restoration of the p53 mediated repression of the AFP promotor activity
Li et al., World J Gastroenterol 2004 (Carcinoma, Hepatocellular...) : Western blot assay also demonstrated that AFP promoted the expression of mutative p53 and p21(ras) proteins, and the increased rate of those proteins was 13.0 %, 39.9 %, and 70.9 %, as well as 35.2 %, 102.6 %, and 46.8 % at 6, 12, and 24 h, respectively, as compared with the control
Lee et al., Mol Cell Biol 1999 (Carcinoma, Hepatocellular...) : HNF-3 protein activates while p53 represses AFP transcription through sequence-specific binding within the previously identified AFP developmental repressor domain