◀ Back to CCR8
CCL1 — CCR8
Pathways - manually collected, often from reviews:
-
KEGG Cytokine-cytokine receptor interaction:
CCL1
→
CCR8
(protein-protein, activation)
-
KEGG Chemokine signaling pathway:
CCL1/CCL11/CCL13/CCL14/CCL15/CCL16/CCL17/CCL18/CCL19/CCL2/CCL20/CCL21/CCL22/CCL23/CCL24/CCL25/CCL26/CCL27/CCL28/CCL3/CCL3L1/CCL3L3/CCL4/CCL4L1/CCL4L2/CCL5/CCL7/CCL8/CX3CL1/CXCL1/CXCL10/CXCL11/CXCL12/CXCL13/CXCL14/CXCL16/CXCL2/CXCL3/CXCL5/CXCL6/CXCL9/IL8/PF4/PF4V1/PPBP/XCL1/XCL2
→
CCR1/CCR10/CCR2/CCR3/CCR4/CCR5/CCR6/CCR7/CCR8/CCR9/CX3CR1/CXCR1/CXCR2/CXCR3/CXCR4/CXCR5/CXCR6/XCR1
(protein-protein, activation)
-
WikiPathways Chemokine signaling pathway:
CCL19/CCL27/CXCL3/CXCL10/XCL1/CXCL9/CCL21/CCL1/CCL11/CCL7/CCL17/CCL20/CCL22/CCL25/CCL27/CCL3/CCL4/CCL5/CCL15/CCL7/CCL15/CXCL3/CXCL5/CX3CL1/CXCL12/CCL19/CCL26/CXCL13/CXCL11/CCL24/PF4/CCL28/CXCL14/PPBP/CCL21/CXCL16
→
CXCR5/CCR6/CXCR2/CXCR3/CXCR4/CCR1/CCR9/CCR1/CCR3/CCR2/CCR4/CCR2/CCR7/CCR8/CCR10/CX3CR1/CXCR2/XCR1/CXCR6
(activation)
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Dip Interaction:
CCL1
—
CCR8
(physical association, experimental interaction detection)
Goya et al., J Immunol 1998*
-
IRef Dip Interaction:
CCL1
—
CCR8
(physical association, experimental interaction detection)
Roos et al., J Biol Chem 1997*
-
IRef Dip Interaction:
CCL1
—
CCR8
(physical association, biochemical)
Nomiyama et al., Int Immunol 2001*
-
IRef Dip Interaction:
CCL1
—
CCR8
(physical association, biochemical)
Howard et al., Blood 2000*
-
IRef Hprd Interaction:
CCL1
—
CCR8
(in vivo)
Gilchrest et al., Life Sci 2003*, Roos et al., J Biol Chem 1997*
-
IRef Hprd Interaction:
CCL1
—
CCR8
(in vitro)
Gilchrest et al., Life Sci 2003*, Roos et al., J Biol Chem 1997*
-
IRef Innatedb Interaction:
CCL1
—
CCR8
(unknown, -)
Roos et al., J Biol Chem 1997*
-
IRef Ophid Interaction:
CCL1
—
CCR8
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
-
IRef Ophid Interaction:
CCL1
—
CCR8
(aggregation, confirmational text mining)
Roos et al., J Biol Chem 1997*
Text-mined interactions from Literome
Louahed et al., Eur J Immunol 2003
(MAP Kinase Signaling System) :
CCR8 dependent activation of the RAS/MAPK pathway
mediates anti-apoptotic activity of I-309/
CCL1 and vMIP-I
Ghosh et al., J Med Chem 2006
:
Activation of
CCR8 by its ligand
CCL1 may play an important role in diseases such as asthma, multiple sclerosis, and cancer