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ADORA1 — NOS1
Text-mined interactions from Literome
Zheng et al., Brain Res 2005
:
Isoflurane preconditioning induced protection against glutamate neurotoxicity was abolished by two protein kinase C ( PKC ) inhibitors, calphostin C ( 0.5 microM ) and chelerythrine ( 5 microM ), or a
nitric oxide synthase (NOS) inhibitor, l-nitro ( G ) -arginine methyl ester ( l-NAME, 1.5 mM ), but was not
affected by an
adenosine A1 receptor inhibitor, 8-cyclopentyl-1,3-dipropylxanthine ( DPCPX, 300 nM ), or a Gi protein inhibitor, pertussis toxin ( PTX, 200 ng/ml )
Cipriani et al., Exp Neurol 2008
(Disease Models, Animal...) :
These findings demonstrate for the first time a
role of
adenosine A ( 2A ) receptors in regulating
nNOS expression in the striatum