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GCHFR — IL12B
Text-mined interactions from Literome
Liu et al., J Exp Med 2003
:
We demonstrate that the levels of IL-12
p35 protein stimulated by IFN-gamma and lipopolysaccharide (LPS) correspond to those of its mRNA, and that the nuclear factor kappaB signaling pathway is
essential for the induction of
IL-12 p35 transcription by LPS
Kricek et al., Eur J Immunol 1995
:
After GAMD injection, two groups of induction profiles were observed in spleen, mesenteric lymph nodes and Peyer 's patches : while IL-4 and
IL-12p35 gene transcription was strongly enhanced, IFN-gamma,
IL-12p40 and IL-13 mRNA were only moderately
induced
Hayes et al., Blood 1995
:
These results indicated that both p40 and
p35 are LPS-inducible in monocytes following IFN-gamma pretreatment, and that the regulated expression of p35
controls the level of active
IL-12 protein in purified human monocytes