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RAC3 — SDC4

Text-mined interactions from Literome

Park et al., Cancer Res 2005 (Fibrosarcoma...) : Consistent with the increased cell migration/invasion of syndecan-2 overexpressing HT1080 cells, syndecan-2 overexpression increased phosphorylation and interaction of focal adhesion kinase ( FAK ) and phosphatidylinositol 3-kinase (PI3K), membrane localization of T-lymphoma invasion and metastasis gene-1 ( Tiam-1 ), and activation of Rac
Carmona-Fontaine et al., Cell Adh Migr 2008 : By analyzing the activity of the small GTPases using in vivo FRET imaging we showed that PCP signaling activates RhoA, while syndecan-4 inhibits Rac , both at the back of the neural crest cell