Gene interactions and pathways from curated databases and text-mining

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PITX1 — RELA

Text-mined interactions from Literome

Kim et al., Eur J Immunol 2006 (Diarrhea) : Suppression of the NF-kappaB signal significantly decreased COX-2 expression in response to BFT stimulation
Kim et al., Clin Exp Immunol 2009 : BFT activated nuclear factor-kappaB (NF-kappaB) signals in HT-29 cells and pretreatment with eupatilin suppressed NF-kappaB activation that resulted in the significant inhibition of IL-8 and cyclo-oxygenase-2 expression ... In addition, herbimycin A, a specific inhibitor of heat shock protein 90 (Hsp90), decreased the BFT induced activation of IKK and NF-kappaB , suggesting that Hsp90 is associated with a pathway of IKK-NF-kappaB-IL-8/cyclo-oxygenase-2 gene signalling