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FOXO3 — RELA

Text-mined interactions from Literome

Mitsiades et al., Oncogene 2002 (Multiple Myeloma) : In contrast, IL-6 does not cause sustained NF-kappaB activation, induces less pronounced Akt activation and FKHRL-1 phosphorylation than IGF-1, and increases the expression of only survivin
Su et al., Immunity 2004 (Lymphoproliferative Disorders) : Another fork in the road : Foxo3a regulates NF-kappaB activation
Lin et al., Immunity 2004 (Hypersensitivity...) : Regulation of NF-kappaB , Th activation, and autoinflammation by the forkhead transcription factor Foxo3a ... Foxo3a inhibits NF-kappaB activation, whose overactivity was responsible for T cell hyperactivity in Foxo3a-deficient mice ... Thus, Foxo3a regulates helper T cell activation and tolerance by inhibiting NF-kappaB activity, reinforcing a generalized role for the forkhead proteins in the maintenance of T cell tolerance through the inhibition of inflammatory transcriptional activities
Terragni et al., BMC cell biology 2008 : Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFkappaB transcription factors
Zhou et al., Gastroenterology 2009 (Colitis...) : Mechanistically, FoxO4 inhibited the transcriptional activity of nuclear factor-kappaB (NF-kappaB) , and Foxo4 deficiency is associated with increased NF-kappaB activity in vivo