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IL8 — SERPINE1

Text-mined interactions from Literome

Audibert et al., Infect Immun 2001 (Helicobacter Infections) : The cag PAI is involved in the ability to induce interleukin-8 (IL-8) secretion by human cells, which is implicated in the inflammatory response of the gastric mucosa to H. pylori infection
Philpott et al., Cell Microbiol 2002 (Disease Models, Animal...) : Six isolates were shown to harbour a complete cag PAI and to induce NF- kappa B activation and IL-8 secretion in AGS cells
Hsu et al., Am J Gastroenterol 2002 (Duodenal Ulcer...) : Although the cag PAI plays an important role in IL-8 production, clinical presentation can not be predicted by the presence of an intact cag PAI or any of these seven cag PAI genes
Dong et al., Hypertens Res 2003 (Acute-Phase Reaction...) : Because the liver is one of the major sources of circulating PAI-1, we here examined the effects of two proinflammatory cytokines, interleukin (IL)-1beta , and IL-6, on PAI-1 production in a human hepatoma cell line, HepG2
Sieveking et al., J Gastroenterol Hepatol 2004 (Helicobacter Infections) : Both IL-8 and GRO-alpha were produced by both AGS and KATO-III cells in response to H. pylori infection, and in a cag PAI dependent manner
Zhang et al., J Clin Microbiol 2005 (Helicobacter Infections...) : cag PaI products induce the secretion of interleukin-8 (IL-8) from epithelial cells and facilitate the translocation of CagA into the cell cytosol
Andrzejewska et al., J Bacteriol 2006 (Helicobacter Infections) : As reported previously, isogenic H. pylori mutants in the putative cag pilin gene had reduced abilities to induce cag PAI dependent interleukin-8 secretion in gastric epithelial cells
Li et al., Arterioscler Thromb Vasc Biol 1997 (Arteriosclerosis...) : The positive control interleukin-1 increased both 2/2 and 1/1 PAI-1 mRNA levels by approximately 5- to 6-fold