Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
Calcineurin Complex/RUNX1 complex (RUNX1)
→
ETS1
(increases, ETS1 Activity, RUNX1 Activity)
Evidence: Mutant analysis of the GM-CSF promoter shows that the Ets1 binding site of the promoter is essential for the synergy between AML1 and CN in Jurkat T cells.
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *