Gene interactions and pathways from curated databases and text-mining

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ETS1 — RUNX1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: Calcineurin Complex/RUNX1 complex (RUNX1) → ETS1 (increases, ETS1 Activity, RUNX1 Activity)
    Evidence: Mutant analysis of the GM-CSF promoter shows that the Ets1 binding site of the promoter is essential for the synergy between AML1 and CN in Jurkat T cells.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *