Gene interactions and pathways from curated databases and text-mining

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BRCA1 — MATK

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Yan et al., Cancer Res 2008 : Moreover, BRCA1 expression is also required for IR-induced ATM and rad3 related activation and Chk1 phosphorylation in MCF-7 cells
Tonic et al., J Biol Chem 2010 : Akt prevents the translocation of BRCA1 to DNA damage foci and, thereby, inhibiting the activation of Chk1 following DNA damage
Yarden et al., Int J Biochem Cell Biol 2012 : BRCA1 dependent Chk1 phosphorylation triggers partial chromatin disassociation of phosphorylated Chk1 and facilitates S-phase cell cycle arrest