Gene interactions and pathways from curated databases and text-mining

◀ Back to CCR1

CCR1 — CXCL14

Pathways - manually collected, often from reviews:

  • KEGG Chemokine signaling pathway: CCL1/CCL11/CCL13/CCL14/CCL15/CCL16/CCL17/CCL18/CCL19/CCL2/CCL20/CCL21/CCL22/CCL23/CCL24/CCL25/CCL26/CCL27/CCL28/CCL3/CCL3L1/CCL3L3/CCL4/CCL4L1/CCL4L2/CCL5/CCL7/CCL8/CX3CL1/CXCL1/CXCL10/CXCL11/CXCL12/CXCL13/CXCL14/CXCL16/CXCL2/CXCL3/CXCL5/CXCL6/CXCL9/IL8/PF4/PF4V1/PPBP/XCL1/XCL2 → CCR1/CCR10/CCR2/CCR3/CCR4/CCR5/CCR6/CCR7/CCR8/CCR9/CX3CR1/CXCR1/CXCR2/CXCR3/CXCR4/CXCR5/CXCR6/XCR1 (protein-protein, activation)
  • WikiPathways Chemokine signaling pathway: CCL19/CCL27/CXCL3/CXCL10/XCL1/CXCL9/CCL21/CCL1/CCL11/CCL7/CCL17/CCL20/CCL22/CCL25/CCL27/CCL3/CCL4/CCL5/CCL15/CCL7/CCL15/CXCL3/CXCL5/CX3CL1/CXCL12/CCL19/CCL26/CXCL13/CXCL11/CCL24/PF4/CCL28/CXCL14/PPBP/CCL21/CXCL16 → CXCR5/CCR6/CXCR2/CXCR3/CXCR4/CCR1/CCR9/CCR1/CCR3/CCR2/CCR4/CCR2/CCR7/CCR8/CCR10/CX3CR1/CXCR2/XCR1/CXCR6 (activation)

Text-mined interactions from Literome

Schwartzkopff et al., Innate Immun 2012 (Inflammation) : We report that the platelet derived CXC chemokine ligand 4 ( CXCL4 ), a known activator of human monocytes, induces down-regulation of CC chemokine receptors (CCR) 1 , -2, and -5, resulting in drastic impairment of monocyte chemotactic migration towards cognate CC chemokine ligands (CCL) for these receptors ... Interestingly, CXCL4 mediated down-regulation of CCR1 , CCR2 and CCR5 was strongly dependent on the chemokine 's ability to stimulate autocrine/paracrine release of TNF-a ... Interestingly, CXCL4 mediated down-regulation of CCR1, CCR2 and CCR5 was strongly dependent on the chemokine 's ability to stimulate autocrine/paracrine release of TNF-a ... Culture supernatants of CXCL4 stimulated monocytes as well as chemokine enriched preparations thereof reproduced CXCL4 induced CCR down-regulation
Lee et al., J Immunol 2012 : CCR1 mediated STAT3 tyrosine phosphorylation and CXCL8 expression in THP-1 macrophage-like cells involve pertussis toxin-insensitive Ga ( 14/16 ) signaling and IL-6 release