Gene interactions and pathways from curated databases and text-mining

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IL18BP — IRF1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Fantuzzi et al., Eur J Immunol 2001 : In conclusion, IRF-1 regulates IL-18 production and activity mostly by modulating expression of caspase-1 and IL-18BP
Marotte et al., Arthritis Rheum 2011 (Arthritis, Rheumatoid) : To examine the role of interferon regulatory factor 1 (IRF-1) in tumor necrosis factor a (TNFa) induced interleukin-18 binding protein a ( IL-18BPa ) expression in rheumatoid arthritis synovial fibroblasts ( RASFs ) ... Control and IRF-1 small interfering RNA ( siRNA ) were used to analyze the effect of IRF-1 down-regulation on TNFa induced IL-18BP expression