Gene interactions and pathways from curated databases and text-mining

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CD4 — MYD88

Text-mined interactions from Literome

Franklin et al., Microbes Infect 2007 (Malaria...) : MyD88 dependent activation of dendritic cells and CD4 ( + ) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria
Zhou et al., J Virol 2009 (Arenaviridae Infections) : Overall, these studies reveal a previously unknown role of MyD88 dependent signaling in CD4 ( + ) T cells in the regulation of the virus-specific CD4 ( + ) T-cell response and in viral infection induced immunopathology in the central nervous system
Letran et al., Eur J Immunol 2011 : Surprisingly, the adaptor molecule Myd88 was not required for robust CD4 ( + ) T-cell responses to flagellin, indicating that TLR5 enhances flagellin-specific CD4 ( + ) T-cell responses in the absence of conventional TLR signaling