Gene interactions and pathways from curated databases and text-mining

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RELA — RPTOR

Text-mined interactions from Literome

Brown et al., Ann Clin Lab Sci 2006 (Neoplasms, Squamous Cell...) : Because the mammalian target of the rapamycin (mTOR) pathway contributes to the activation of NF-kappaB through immunophilin/mTOR signaling , we investigated : ( a ) the immunohistochemical expression and state of activation and potential clinical significance of components of the mTOR signal transduction pathway in SCCT patients ( morphoproteomics ) ; and ( b ) the inhibitory effects of rapamycin on the growth and state of activation of mTOR in 2 HNSCC cell lines ( pharmacoproteomics )
Dan et al., Genes Dev 2008 (Prostatic Neoplasms) : Akt dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK ... The mTOR associated protein Raptor is required for the ability of Akt to induce NF-kappaB activity