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FCER2 — RELA

Text-mined interactions from Literome

Hsing et al., J Immunol 1999 : Surprisingly, up-regulation of Fas, CD23 , and ICAM-1 was partially independent, and up-regulation of LFA-1 was completely independent , of CD40 induced NF-kappaB activation
Ten et al., J Allergy Clin Immunol 1999 : CD23 induced NF-kappaB is a heterodimer composed of p65/p50 subunits
Ten et al., J Immunol 1999 : Investigation of the second messengers mediating the CD23 dependent activation of NF kappa B demonstrates that I kappa B kinases ( IKKs ) but not p90rsk are selectively activated following CD23 cross linking and mediates the phosphorylation of I kappa B alpha ... Cotransfection experiments with an IKK beta negative dominant completely inhibit CD23 induced NF kappa B activation ... Furthermore, the activation of tyrosine kinase ( s ) by CD23 is required for the induction of IKK activity, I kappa B alpha degradation, and NF-kappa B nuclear translocation ... Taken together, our results show that CD23 cross linking in the monocytic lineage induces tyrosine kinase activation followed by activation of IKK, which phosphorylates I kappa B alpha at the N-terminal domain ( Ser32/Ser36 ), inducing its degradation, NF-kappa B activation and gene transcription
Mitsuta et al., Allergy Asthma Proc 2003 (Asthma...) : Our results indicated that TNF-alpha production was induced by D. farinae in PBMCs of patients with atopic asthma by the activation of NF-kappa B via CD23
Tinnell et al., Int Immunol 1998 : Based on these data, a model is presented which suggests that CD23 superinduction results from STAT and NF-kappaB interaction