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HSPG2 — NPPA

Text-mined interactions from Literome

Mouawad et al., Mol Pharmacol 2004 : C-ANP ( 4-23 ) [ des ( Gln ( 18 ), Ser ( 19 ), Glu ( 20 ), Leu ( 21 ), Gly ( 22 ) ) ANP ( 4-23 ) -NH ( 2 ) ], a ring deleted peptide of ANP that interacts specifically with ANP-C receptor, stimulated inositol 1,4,5-tris-phosphate ( IP ( 3 ) ) production ( PLC activity ) in A10 vascular smooth muscle cells in a concentration- and time dependent manner
Berl et al., Am J Physiol 1991 : We examined the possibility that, in addition to stimulation of guanylate cyclase ( GC ), atrial natriuretic peptide (ANP) also activates phospholipase C (PLC) in cultured rat inner medullary collecting tubule ( RIMCT ) cells ... Therefore, activation of cyclic nucleotide dependent protein kinase inhibits ANP stimulated PLC activity ... We conclude that ANP stimulates PLC in RIMCT cells via a pertussis toxin-sensitive G protein