Hu et al., J Invest Dermatol 2008
(Adenocarcinoma...) :
We further demonstrated that Tie2-R849W chronically induced STAT1 tyrosine phosphorylation and the promoter activity of STAT1-responsive IFN-regulatory factor 1 (IRF1)
Huang et al., Angiogenesis 2013
(Vascular Malformations) :
STAT1 activation by venous malformations mutant Tie2-R849W antagonizes VEGF-A mediated angiogenic response partly via reduced bFGF production ... Tie2-R849W* induced STAT1 phosphorylation at Tyr701