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CDK9 — STAT3

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: STAT3 → Complex of CDK9-STAT3 (directlyIncreases, CDK9/STAT3 Activity)
  Evidence: Several studies have suggested that STAT3 prevents cell-cycle arrest and cell death through upregulation of survival proteins and downregulation of tumor suppressors. STAT3 proteins act as transcriptional activators and activate their target genes through their association with several coactivator complexes such as steroid receptor coactivator 1 (NCOA) SRC1a, cyclin-dependent kinase 9 (CDK9) or Brahmarelated gene 1 (BRG1)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: CDK9 — STAT3 (physical association, affinity chromatography technology) Giraud et al., Oncogene 2004*
• IRef Biogrid Interaction: CDK9 — STAT3 (direct interaction, pull down) Giraud et al., Oncogene 2004*