Gene interactions and pathways from curated databases and text-mining

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C5 — STAT3

Text-mined interactions from Literome

Niculescu et al., Immunopharmacology 1999 : Tyrosine phosphorylation and activation of Janus kinase 1 and STAT3 by sublytic C5b-9 complement complex in aortic endothelial cells ... However, phosphorylation of STAT3 was not inhibited by Pertussis toxin, although C5b-9 induced a time dependent nuclear translocation of STAT3
Niculescu et al., Mol Immunol 1999 (Arteriosclerosis...) : JAK1 but not STAT3 activation induced by C5b-9 is dependent on Gi protein activation
Niculescu et al., Immunol Res 2001 : PI3-K activation by C5b-9 induced STAT3 phosphorylation and translocation from cytoplasm to nucleus