Gene interactions and pathways from curated databases and text-mining

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CLDN2 — IL13

Text-mined interactions from Literome

Weber et al., J Biol Chem 2010 (Inflammatory Bowel Diseases) : In contrast, IL-13 dependent claudin-2 expression increases paracellular cation flux in vitro and in vivo without altering tight junction size selectivity but is unaffected by MLCK inhibition in vitro
Rosen et al., Inflamm Bowel Dis 2011 (Colitis, Ulcerative...) : Cell transfection with STAT6 siRNA prevented IL-13 induced apoptosis and claudin-2 expression ... SAHA inhibited IL-13 induced STAT6 phosphorylation, apoptosis, and claudin-2 expression, and mitigated IL-13 induced reductions in transepithelial resistance
Rosen et al., J Immunol 2013 (Colitis, Ulcerative...) : Similarly, short hairpin RNA STAT6 knockdown reduced claudin-2 induction and transepithelial resistance decrease in IL-13 treated human T84 cells