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CAT — NOS3
Text-mined interactions from Literome
Drummond et al., Circ Res 2000
:
Induction of
eNOS by H ( 2 ) O ( 2 ) was not affected by the hydroxyl radical scavenger DMSO, mannitol, or N-tert-butyl-alpha-phenylnitrone, but it was
inhibited by the antioxidants N-acetylcysteine, ebselen, and exogenously added
catalase ... Unlike H ( 2 ) O ( 2 ), the 4.0-fold induction of
eNOS by shear stress ( 15 dyne/cm ( 2 ) for 6 hours ) was not
inhibited by N-acetylcysteine or exogenous
catalase
Jang et al., Biochem Pharmacol 2004
:
Catalase induces the expression of inducible
nitric oxide synthase through activation of NF-kappaB and PI3K signaling pathway in Raw 264.7 cells
Dong et al., Diabetologia 2006
(Insulin Resistance) :
Catalase ablated insulin-resistance induced mechanical dysfunction, ROS production and protein damage, and
reduced eNOS , but not insulin insensitivity
Lorenz et al., Basic Res Cardiol 2009
:
Whereas stimulation of eNOS activity by EGCG was only slightly affected by pretreatment of cells with various ROS scavengers, TF3 ( theaflavin-3',3-digallate ) -induced
eNOS activity was partially
inhibited by
PEG-catalase
Kumar et al., Am J Physiol Lung Cell Mol Physiol 2010
:
We also found that the overexpression of
catalase significantly
attenuated the shear mediated increases in H2O2, phospho-Ser1177
eNOS , and NO generation
Dao et al., J Cell Mol Med 2011
:
These data suggest that physiological venous
catalase activity
prevents exercise induced up-regulation of
eNOS and ecSOD
Rengasamy et al., Biochem Pharmacol 1994
:
Effect of hydrogen peroxide and
catalase on rat cerebellum
nitric oxide synthase ... The
effect of H2O2 and
catalase on isolated rat cerebellum
nitric oxide ( NO ) synthase activity was determined by measuring the conversion of L- [ 3H ] arginine to L- [ 3H ] citrulline
Rotzinger et al., Life Sci 1995
:
The
nitric oxide synthase inhibitor NW-nitro-L-arginine methylester
attenuates brain
catalase activity in vitro