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MYLIP — NOTCH2
Text-mined interactions from Literome
Li et al., Cancer Res 2009
(Brain Neoplasms...) :
Transfection of
miR-34a down-regulated c-Met in human glioma and medulloblastoma cells and Notch-1,
Notch-2 , and CDK6 protein expressions in glioma cells ...
miR-34a expression
inhibited c-Met reporter activities in glioma and medulloblastoma cells and Notch-1 and
Notch-2 3'-untranslated region reporter activities in glioma cells and stem cells
Guessous et al., Cell cycle (Georgetown, Tex.) 2010
(Brain Neoplasms...) :
We showed that c-Met and
Notch partially
mediate the inhibitory effects of
miR-34a on cell proliferation and cell death
Nicoli et al., Dev Cell 2012
:
miR-221 knockdown also prevented `` hyper-angiogenesis '' defects associated with Notch deficiency and
miR-221 expression was
inhibited by
Notch signaling
Bae et al., Hum Mol Genet 2012
(Osteoporosis...) :
Furthermore,
miR-34c mediated post-transcriptional regulation of
Notch signaling in osteoblasts is one possible mechanism to modulate the proliferative effect of Notch in the committed osteoblast progenitors which may be important in the pathogenesis of osteosarcomas
Huang et al., BioMed research international 2013
:
Since Notch signaling could inhibit muscle differentiation, a process in contrast with the effect of miR-1,
miR-1 mediated repression of
Notch signaling may contribute to the observed effects of miR-1 in mesenchymal stem cells
Jiang et al., Hypertension 2013
:
In human endothelial cells, loss of
miR-30a increased DLL4 protein levels,
activated Notch signaling as indicated in Notch reporter assays, and augmented Notch downstream effector, HEY2 and EFNB2 ( ephrin-B2 ), expression