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CDKN1A — ID3

Text-mined interactions from Literome

Forrest et al., J Biol Chem 2004 : We demonstrate that Id3 is expressed early in lesion formation when the proliferative index of the neointima is highest and that Id3 promotes smooth muscle cell ( SMC ) proliferation and S-phase entry and inhibits transcription of the cell-cycle inhibitor p21 ( Cip1 )
O'Brien et al., Cancer Cell 2012 (Colonic Neoplasms) : Regulation of p21 by ID1 and ID3 is a central mechanism preventing the accumulation of excess DNA damage and subsequent functional exhaustion of CC-ICs
Sharma et al., Cancer medicine 2012 : Moreover, through gene silencing approaches we show that Id1 and Id3 primarily attenuates CDKN1A ( p21 ) and CDKN1B ( p27 ), respectively