◀ Back to MMP2

IKBKB — MMP2

Text-mined interactions from Literome

Yan et al., Cancer Res 2008 (Carcinoma...) : In addition, SRC-3/AIB1 directly regulates transcription of matrix metalloproteinase (MMP)-2 and MMP-13 through its coactivation of AP-1 and PEA3
Liu et al., Chinese journal of cancer 2010 (Neoplasm Invasiveness...) : Moreover, the inhibition of IKKbeta inhibited the expressions of MMP-2 and MMP-9 ... IKKbeta may play a crucial role in the OPN induced activation of MMP-2 and MMP-9 via NF-kappaB mediated IkappaB/IKKbeta pathways
Liu et al., Cancer Lett 2010 (Prostatic Neoplasms) : Moreover, the inhibition of IKK-2 can suppress MMP-2 and MMP-9 expressions, in contrast, the inhibition of IKK-1 has no effects on the OPN, MMP-2 and MMP-9 expression levels ... Thus, this study demonstrated that OPN knockdown could downregulate MMP-2 and MMP-9 expressions result in inhibiting the malignant physiological behaviors of PC-3 cell and that IKK-2 may play a crucial role in OPN induced MMP-2 and MMP-9 expressions via NF-kappaB mediated signaling pathways