◀ Back to EGF

EGF — GTPBP8

Text-mined interactions from Literome

Hart et al., J Biol Chem 1990 : The identification and characterization of an epidermal growth factor stimulated phosphorylation of a specific low molecular weight GTP binding protein in a reconstituted phospholipid vesicle system ... The EGF stimulated phosphorylation of this GTP binding protein is also markedly attenuated by guanine nucleotides, i.e. GTP, GTP gamma S, or GDP, suggesting that maximal phosphorylation occurs when the GTP binding protein is in a guanine nucleotide depleted state ... When highly purified preparations of the human platelet Gp ( G25K ) protein are reconstituted with the purified EGF receptor into phospholipid vesicles, an EGF stimulated phosphorylation of the platelet GTP binding protein occurs with a stoichiometry approaching 2 mol of 32Pi incorporated/mol of [ 35S ] GTP gamma S-binding sites ... As is the case for the brain 22-kDa protein, the EGF stimulated phosphorylation of the platelet GTP binding protein is attenuated by guanine nucleotides
Simpson et al., Nat Cell Biol 2012 : Network analyses revealed a so far unappreciated link between early secretory pathway function, small GTP binding protein regulation , actin cytoskeleton organization and EGF-receptor mediated signalling
Kuryshev et al., Cell Signal 1993 : Evidence for involvement of a GTP binding protein in activation of Ca2+ influx by epidermal growth factor in A431 cells : effects of fluoride and bacterial toxins