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CREBBP — FOS

Pathways - manually collected, often from reviews:

• NCI Pathway Database FOXA1 transcription factor network: nucleus (EP300/CREBBP) → AP1 complex (FOS-JUN) (transcription, activates) Eeckhoute et al., Genes Dev 2006
  Evidence: mutant phenotype, reporter gene, physical interaction
• NCI Pathway Database HIF-1-alpha transcription factor network: AP1 complex (FOS-JUN) → nucleus (EP300/CREBBP) (transcription, activates) Yamashita et al., J Biol Chem 2001
  Evidence: mutant phenotype, reporter gene, physical interaction

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: FOS — CREBBP (physical association, affinity chromatography technology) Bossis et al., Mol Cell Biol 2005*
• IRef Biogrid Interaction: FOS — CREBBP (direct interaction, pull down) Fan et al., Cancer Res 2002*

Text-mined interactions from Literome

O'Connor et al., J Virol 1996 : We also provide data demonstrating that YY1 can bind the transcriptional coactivator CREB binding protein and propose a potentially novel mechanism by which YY1 represses AP-1 activity as a result of this YY1-CREB binding protein interaction
Lee et al., Cell Growth Differ 1997 (Carcinoma, Non-Small-Cell Lung...) : Furthermore, the inhibitory effect of t-RA on AP-1 transcriptional activity was not restored in tumorigenic 11701 cells by transfection of c-fos, silencing mediator for retinoid and thyroid hormone receptors, Jun activation domain binding protein 1, or CREB binding protein , suggesting the involvement of other transcriptional coregulators in this retinoid signaling defect