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ABR — RAC1

Pathways - manually collected, often from reviews:

• NCI Pathway Database Regulation of RAC1 activity: ABR (ABR) → RAC1/GTP complex (RAC1) (modification, activates) Cho et al., Mol Cell Biol 2007*
  Evidence: mutant phenotype, assay, other species
• NCI Pathway Database Regulation of RAC1 activity: ABR (ABR) → RAC1/GDP complex (RAC1) (modification, activates) Cho et al., Mol Cell Biol 2007*
  Evidence: mutant phenotype, assay, other species
• Reactome Reaction: RAC1 → ABR (reaction) Harrington et al., J Neurosci 2002

Text-mined interactions from Literome

Yi et al., J Biol Chem 2009 (Celiac Disease...) : Bcr and the closely related Abr negatively regulate the small G-protein Rac : loss of their combined function in vivo results in increased reactivity of innate immune cells
Oh et al., J Neurosci 2010 (Synaptic Transmission) : These results suggest that BCR and ABR have novel roles in the regulation of synaptic Rac1 signaling, synaptic plasticity, and learning and memory, and that excessive Rac1 activity negatively affects synaptic and cognitive functions