Gene interactions and pathways from curated databases and text-mining

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IL1A — LRP1

Text-mined interactions from Literome

Noguchi et al., Biochem Biophys Res Commun 2001 : These results revealed that low-density lipoprotein receptor related protein ( LRP ), which is known to be a receptor for tPA and to be blocked by RAP, was up-regulated by IL-1 ... We also demonstrated, for the first time, that IL-1 transiently increased the mRNA level of LRP threefold by 30 min after the start of IL-1 treatment of AML 12
Tucker et al., Am J Respir Cell Mol Biol 2012 : These studies indicate that TNF-a and IL-1ß regulate LRP-1 in PMCs and that LRP-1 thereby contributes to a range of pathophysiologically relevant responses of these cells